tag:blogger.com,1999:blog-6780103924890350442.post2916867528628536336..comments2023-11-30T00:29:08.106-08:00Comments on Animal Pharm: Hypertension and the X-ImageDr. B Ghttp://www.blogger.com/profile/15451872961651116061noreply@blogger.comBlogger31125tag:blogger.com,1999:blog-6780103924890350442.post-87181723303082820432010-07-06T10:52:51.404-07:002010-07-06T10:52:51.404-07:00Old age: when things that used to be flexible get ...Old age: when things that used to be flexible get stiff, and things that used to be stiff get flexible :(<br /><br />From that POV insulin resistance = ageingAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-23021931711446226962010-02-16T17:21:18.775-08:002010-02-16T17:21:18.775-08:00lightcan,
I need Lp(a) for dummies after Peter...lightcan,<br /><br />I need Lp(a) for dummies after Peter's post too! It is nice to understand the putative mechanisms underlying this factor (as is sdLDL) and how evolution plays in.<br /><br />Like many out there in the blogosphere, nothing makes sense unless it is in 'light of evolution'... that is what Billy E and Dr. Tourgeman and I purport.<br /><br />Don't worry I knew you were being facetious... I think Lp(a) is a big challenge at TYP and with Heart Hawk (at any Lp(a) level 2-200+ mg/dl) but I don't think Davis was implying for himself (although course he is quite intelligent for being a recovering vegetarian; I give him a lot of credit for accepting change).<br /><br />Lightcan -- you don't give yourself enough credit!!<br /><br />Do you have a baseline Lp(a) prior to paleo? Has it improved? I have seen easy improvements from mid-100s to 200s with 50-70% drops in just 4wks with dietary changes (and pounding some fish oil)... <br /><br />I think the goal is nice fluffy particles, not dense st*pid stuff. Like LDL, if Lp(a)/oxLDL is high accompanied by high insulin, high insulin resistance, low HDLs, high Tgs, high sdLDL, then the Lp(a)/oxLDL is all likely to be the dense stuff as well. Studies show that soft plaque may have a core interior of oxLDL (e.g. Lp(a)) whcih is not calcified yet -- but HIGHLY unstable and likely to rupture/clot and thus be more likely to cause imminent infarctions (strokes/heart attacks).<br /><br />But of course controllable! :) Within 2-4wks of low carb, high sat fat paleo (and some vit D/omega-3 and thyroid improvements)<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-8405618538477901532010-02-16T16:44:23.816-08:002010-02-16T16:44:23.816-08:00Dr. Harris from PaNu
Yes, Peter is brilliant and ...Dr. Harris from PaNu<br /><br />Yes, Peter is brilliant and cool, but I am not sure I understood everything. I need 'Lp(a) for dummies'!<br /><br />Oh, re. Clinton, that was a joke and a propositional fallacy. Just because I have high lp(a) doesn't mean I am very intelligent.lightcanhttps://www.blogger.com/profile/03050215395108869677noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-79997996722165395702010-02-16T08:09:57.824-08:002010-02-16T08:09:57.824-08:00Hey lightcan,
It is true -- I think Lp(a) carrier...Hey lightcan,<br /><br />It is true -- I think Lp(a) carriers are amazing survivors and have uncanncy intelligence. See lightcan -- you ARE a PRIME example *wink* and I wish I had some!<br /><br />Even if Clinton's Lp(a) was ~10 mg/dl -- that would be uncontrolled on the low saturated fat SAD (which is probably what he was following lately). Honestly the saturated fat from McDonald's and midwestern cooking is probably what protected the coronary vessels from not blocking up in his younger 40s-50s, I would conjecture.<br /><br />Mainly only saturated fat, omega-3s, and low carb control Lp(a). <br /><br />Saturated fatty acids also control infections -- they are vital to our immunity along with omega-3 fatty acids. Lp(a) is an 'arm' of the immune system just like HDLs and LDLs.<br /><br />I think Peter's series on Lp(a) is ASTOUNDING and nothing he writes on cardiovascular disease is short of pure BRILLIANCE. <br /><br />His latest is great:<br />http://high-fat-nutrition.blogspot.com/2010/02/ok-ascorbate-and-lpa.html<br /><br />We all have more to learn... I am not so into heart disease anymore b/c it is TOTALLY reversible and simple to do: <br />--low carb Paleo<br />--fix vitamin/hormone deficiencies<br />--exercise<br />--EAT SATURATED FAT D*MN IT TO INCR HDL2b, immunity AND CONTROL Lp(a)<br /><br /><br />Dr. Harris? Do you mean the omega-3 index guy?<br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-67053532739767658942010-02-16T04:56:24.206-08:002010-02-16T04:56:24.206-08:00Uh, this has been the funniest thing I've seen...Uh, this has been the funniest thing I've seen in ages: Dr. Davis on Clinton and his stent. 'Lp(a) tends to be the province of people with greater than average intelligence.' ergo my super high Lp(a) means I am very intelligent? I wouldn't say so myself, (not much more than 120 I guess), but dr. Harris definitely is. <br /><br />What is the take home message from Peter's posts? Have you changed your position, re. your assertion than any lp(a) is bad (Hecht)?lightcanhttps://www.blogger.com/profile/03050215395108869677noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-76433967508271977942010-02-14T21:14:35.075-08:002010-02-14T21:14:35.075-08:00Gongxi Facai Mary!
I love the ginger syrup w/douh...Gongxi Facai Mary!<br /><br />I love the ginger syrup w/douha too but it makes my heart race from the sweetness(!). Mafia have a way of surviving don't they?<br /><br />Gan xia! Ni ti ke qi!! Da jihui. It is an truly exciting opportunity to evolve healthcare. <br /><br />Peace and prosperity,<br />GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-91209782306441477042010-02-14T12:53:03.791-08:002010-02-14T12:53:03.791-08:00gongxi facai!!
oh no! i just had douhua with the ...gongxi facai!!<br /><br />oh no! i just had douhua with the syrup and i have a yucky feeling in my chest!!! my daughter warned me. anyway tea lunch was yummy and we saw some good dragon dancers and kung fu artists, after which my husband and the douhua lady informed me they were affiliated with with the local chinatown mafia who collect about $100 a month from stores for 'protection' (zai bingzhou, feicheng). rule of law isn't always the general rule.<br /><br /> gongxi yisheng yao zanjia 2011 nian paleo/ancenstral eating da hui. hen guangrong o!v/vmaryhttps://www.blogger.com/profile/06862544306715636777noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-68895100869259351642010-02-14T11:29:53.282-08:002010-02-14T11:29:53.282-08:00lightcan!
Happy Lunar Chinese New Year to YOU my ...lightcan!<br /><br />Happy Lunar Chinese New Year to YOU my gal (and all the other sexxxxxy HOT animals out there)!<br /><br />May it be a truly blessed year *wink*<br /><br />XOXOXO,<br />GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-13964964893603211692010-02-14T09:24:15.033-08:002010-02-14T09:24:15.033-08:00Happy Year of the Tiger, our special tigress!!Happy Year of the Tiger, our special tigress!!lightcanhttps://www.blogger.com/profile/03050215395108869677noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-54827810170642453172010-02-11T08:51:04.227-08:002010-02-11T08:51:04.227-08:00Peter,
JE Schneider is amazing -- I thought you m...Peter,<br /><br />JE Schneider is amazing -- I thought you might appreciate her inter-species discussions. Especially the bipedal, big cranium, small gut animal species.<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-79269124989222084532010-02-11T08:49:49.413-08:002010-02-11T08:49:49.413-08:00Neomide!
I'll ck out the Vasquez link -- than...Neomide!<br /><br />I'll ck out the Vasquez link -- thanks!<br /><br />We ARE telepathic :) *ahaa*<br /><br />Sorry about the Finland news -- I guess fats will remain controversial everywhere for another oh... what? 50 yrs? Or is it time soon?! *heee*<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-40621505391031336562010-02-11T03:06:46.402-08:002010-02-11T03:06:46.402-08:00G,
Just catching up here. Some great links. Fanta...G,<br /><br />Just catching up here. Some great links. Fantastic stuff!<br /><br />PeterPeterhttps://www.blogger.com/profile/14527788116058656094noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-53235738844179419312010-02-10T18:31:31.336-08:002010-02-10T18:31:31.336-08:00Bootylicious!
I was just warming up my own paleo ...Bootylicious!<br /><br />I was just warming up my own paleo post on fasting insulin and wondered the link with hypertension. Thank You again so much for so many steaming hot references on the subject!<br /><br />I was "diagnosed" with elevated BP as a child (no reason given), so hypertension discussion is always of interest to me. No white coat syndrome, I'm afraid. Seems that I'm a Vitamin D hyper responder on hypertension like I told before, yet I agree that many other things also come to play. Other than sodium restriction and exercise, I'm sure. It seems we're having a telepathic connection!<br /><br />Paleo Lifestyle™ sure covers a wide range of strategies! ^^<br /><br />Vitamin D guru James Dowd seems to like magn, Vit D and potassium combo a lot with fresh produce and fish and I'm all into that. Close to DASH in some respects, excluding Whole Grain sh** I' more and more unfond of. (2 months STRAIGHT total avoidance now and I feel great!)<br /><br />A Vit D Council president John Cannell collaborator naturopath Alex Vasquez has a nice list of his take on about Hypertension treatment without drugs, if you are interested:<br /><br />http://www.naturopathydigest.com/archives/2006/nov/vasquez.php<br /><br /><br />PS: Bad News from Finland part deux: the same bloke who has told us that "carbohydrates are more natural food than fat" is the new Professor of Nutrigenomics and Nutrigenetics in our university. He's owned by Nordic Sugar bureau Danesco. I'm a bit afraid we're not getting raunchy stuff like FUNGENUT anytime soon on air. There is always hope.Neonomidehttps://www.blogger.com/profile/00961709424324961929noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-78324929127824639842010-02-10T11:32:11.015-08:002010-02-10T11:32:11.015-08:00mary aka 'V'
Bu ke qi!
holymoly u crack m...mary aka 'V'<br /><br />Bu ke qi!<br />holymoly u crack me up GRRRLL...<br /><br />dui bu qi, ni bu dui -- wo shi wang ba DAN. *haaa*<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-11960672269447723922010-02-10T10:57:16.928-08:002010-02-10T10:57:16.928-08:00i really appreciate your detailed response. you ar...i really appreciate your detailed response. you are the star of the paleo blogs, and i'm not being facetious. i want to have blood work done in april. i lost a lot of tummy fat on paleo since i had that blood work i mentioned, so i will be on the look out for hopefully better liver panel numbers. you're the best!! ni shi zui hao de!! -mary/ aka 'v'v/vmaryhttps://www.blogger.com/profile/06862544306715636777noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-85721662083740258672010-02-10T08:52:07.646-08:002010-02-10T08:52:07.646-08:00btw what I see is when people go low carb and/or s...btw what I see is when people go low carb and/or semi-paleo, the ALT AST goes to lower levels within 4wks. Abnormal normalizes to < 40 and 'normal' 20s 30s will go to < 15. Those to me are signs of an uncongested, visceral fat-free liver organ. At one time mine was as high as 27 when I was getting over some hormone madness (the Levonorgestrel IUD). WTF. A lotta things can cause IR. See Stephan's latest post too. Caffeine, fructose, Mg++ deficiency. I'd add excessive alcohol, n-6 (too many nuts/seeds, especially if unsoaked), dairy (immunogenic effect, all except ghee where proteins are removed).Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-43882414442546066842010-02-10T08:42:18.813-08:002010-02-10T08:42:18.813-08:00Hey Mary,
That liver test is not normal. But I ha...Hey Mary,<br /><br />That liver test is not normal. But I have no evidence.<br /><br />I've seen a couple of cases of NASH and the liver tests were better than yours (< 20).<br /><br />I think 2 things can be going on --(a) intraabdominal visceral fat deposition without enzyme disruption<br />(b) intraabdominal visceral fat deposition with enzyme disruption<br /><br />Sometimes an abdom ultrasound or CT will pick up. Sometimes they don't. (usually it can though but I don't know the specificity or sensitivity b/c liver biopsy is the gold standard for NASH at this time, I believe).<br /><br />Who is predisposed to NASH which is basically insulin resistance at the liver level? Asians, Indo-Asians, Pacific Islanders and all those also predisposed to diabetes Type 2. E.g. 80% of the whole global world. <br /><br />I agree with you -- hormones like estrogen that peak at ovoluation -- shut off insulin resistance (IR) like a 'switch'. Us grrrls can have more IR for no apparent reason other than our bodies think they are preparing for a BABY. *haaa*<br /><br />My only conclusion is that hormones can be very complicated and that the best situation for IR and longevity are optimal 'youthful' levels.<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-70248311498975878682010-02-09T18:59:57.317-08:002010-02-09T18:59:57.317-08:00re what byron said about coconut oil and a carb-li...re what byron said about coconut oil and a carb-like binge- i had the same thing with coconut milk. i put down a whole can of it, even though my stomach was uncomfortably full, like i used to do with a carb binge. this happened several times.<br /><br />then what's weider is as soon as i got my period it was like a light switch going off. i had lost the craving, although i still put a little coconut milk in my coffee. there might be some hormone thing going on with the heavy saturated fat content???<br /><br />anyway- we are having a discussion at paleonu.com, and i was wondering if anyone had anything to add. from that blog, me as 'v' talking to KGH, dr. harris:<br /><br />over at paleonu.com we are discussing 'broken metabolism'. dr. harris thinks the liver is the principally damaged organ here. i told him that my liver panel was normal, but i felt that my metabolism was out of whack last year (pre-paleo). below is some of our conversation. 'KGH' is dr. harris, a radiologist. any thoughts?<br /><br />from paleonu.com:<br /><br />from a couple posts up:<br /><br />v: if the liver is being metabolically damaged from food- the damage has to be already severe for it to be picked up by standard tests for liver function. would you agree with the preceding statement?<br /><br />KGH: No AST and ALT are pretty sensitive. They can go up long before the damage is severe.<br /><br />now v says:<br /><br />i dug up my 5/09 lab results.<br /><br />AST: 21 IU/L out of a normal range ( or "reference interval") of 0-40<br />ALT: 16 IU/L out of a normal range of 0-40<br /><br />So from the liver everything is looking good, right?<br /><br />My TSH was 2.464. High is >3, so TSH looks good<br /><br />But then my Ferritin, Serum is flagged low at 6 ng/mL out of a reference interval of 10-291<br />During this time I had heavy periods, so I suppose all my iron was leaking out. I had cameras go down my throat and up my butt, but no leaking found. They thought maybe I wasn't absorbing iron well, and so tested for celiac: negative. Then they saw my h.pylori bacteria count was high, and knocked it out in January of that year with strong antibiotics. my ferritin had gone up to 25 with iron supplementation. i stopped taking it, and it went back down to 7. my vitamin d was 24 ng/mL, which is low. my Hemogloin A1c was 5.9- a healthy adult is supposed to be 4.8-5.9. my c-reactive protein was 1.48mg/L Average is 1.00 - 3.00. I don't know if any of this jumps out at anyone.<br /><br />I just think it strange that my AST and ALT Liver panel numbers were good, yet my insulin was not stellar, i had an apple shape, and my ferritin level was low with heavy periods.<br /><br />If, by your logic, the liver is the principal damaged organ with a damaged metabolism, and my liver numbers were good, that must mean that my apple shape, low ferritin, and high end of normal insulin are signs of a well-running metabolism, no? But that doesn't make sense. That's why I keep posting about this. Maybe the first organ system to show obvious signs of a damaged metabolism in women is the reproductive system.v/vmaryhttps://www.blogger.com/profile/06862544306715636777noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-53361194423036639552010-02-09T17:17:59.138-08:002010-02-09T17:17:59.138-08:00Bella CIAO!
I still have not wrapped my head arou...Bella CIAO!<br /><br />I still have not wrapped my head around insulin resistance and fat intake. Certainly it makes sense but the studies show no increase in insulin if the diet is paleo (frasetto's) or low carb or no carb (see Ai M's study) with oral glucose load tested against oral fat load.<br />http://drbganimalpharm.blogspot.com/2009/12/insulin-and-aging-how-paleo-works.html<br /><br />Also probably gender, leptin and adiponectin and ghrelen differences exist. <br /><br />I just don't know what they are...<br /><br />*aaah ha* Let me know when you figure it out in your pretty head!!<br /><br />What I know is that when I routine do 3-5 hrs cardio (low intensity) and my sprints/HIIT/xfit 1-2 hrs/wk, then I have no hunger. <br /><br />my food/alcohol intake can be ANYTHING and I still lose weight or maintain. however when I stop the exercise or cut in half, all bets r off *sigh* BUGGERS. Can't have my cupcakes... *haaa* My husband feels like #1 [in the dark *wink* j/k]<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-63355590989189642282010-02-08T22:31:57.481-08:002010-02-08T22:31:57.481-08:00Ciao, BG!
Most excellent post!
Here is a quote fro...Ciao, BG!<br />Most excellent post!<br />Here is a quote from that leptin book I just checked out..<br />"When fat is eaten it stimulates the intestinal tract to release gastric inhibitory peptide that causes insulin to rise leading to insulin resistance.<br />Thus, high fat diets which are not supposed to cause insulin resistance are just as capable of inducing the same problem through a different mechanism."<br />Can you comment on that, cos I just don't know enough about all this stuff yet.. and I can't be arsed to look it up.<br />Is it all down to a clogged, congested and confused liver maybe???????????<br />Hah!<br />The one in the middle looks just like my husband, by the way, [when I'm not wearing my glasses :) ]<br />And the sexiest bit of a man is still the bit between his ears... doesn't matter how buff he is if he opens his mouth and he's got a squeaky voice or talks cr@p!xhttps://www.blogger.com/profile/14809802792206636250noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-24608646905093707142010-02-08T06:34:16.767-08:002010-02-08T06:34:16.767-08:00Aaron,
Happy Tiger Year! *ROAR*
You DEFINITELY h...Aaron,<br /><br />Happy Tiger Year! *ROAR*<br /><br />You DEFINITELY have your X-game on! No more vampire days for you.<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-54087919551017911392010-02-08T06:30:15.056-08:002010-02-08T06:30:15.056-08:00Mike,
Hey hawwwtness you stumped me again. I hav...Mike,<br /><br />Hey hawwwtness you stumped me again. I have too that up -- I'm sure Kenny T. knowns b/c aldosterone is involved in our mineral secretion/retention and the kidneys. MMmmhhh...<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-68843959399456907032010-02-08T06:29:17.330-08:002010-02-08T06:29:17.330-08:00James,
RIGHT ON! Functional full body!
-GJames,<br /><br />RIGHT ON! Functional full body!<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-28224512291733509822010-02-08T06:28:43.416-08:002010-02-08T06:28:43.416-08:00Hey Keith,
You are lucky you didn't end up wi...Hey Keith,<br /><br />You are lucky you didn't end up with full blown something like diabetes. There are so many people who try to do there best just like you were!!!! *sigh*<br /><br />I'd like to blow up that st*pid pyramid.<br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-76832386714100347582010-02-08T06:26:31.906-08:002010-02-08T06:26:31.906-08:00Byron,
BABE! Yes n-6 increases insulin and insul...Byron,<br /><br />BABE! Yes n-6 increases insulin and insulin resistance. I dunno the mechanism but probably involves membrane signalling.<br /><br />Absolutely -- I think casein/casomorphines have multiple routes of raising insulin/IR. Leaky gut has got the be the most (slowly) lethal. Painful for those with GI issues and IBS and fullblown celiac.<br /><br />Coconut oil alone makes me hungry make because it smells so good and it's not a neutral tasting oil like MCT or light olive oil that Shangri La talks about (though others are repulsed/ allergic like kryptonite *haa*).Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.com