tag:blogger.com,1999:blog-6780103924890350442.post562138189468911684..comments2023-11-30T00:29:08.106-08:00Comments on Animal Pharm: The Gut Guardians Podcast: Episode 03 – "Redefining Human" Movie w/ Jamie BinnsDr. B Ghttp://www.blogger.com/profile/15451872961651116061noreply@blogger.comBlogger35125tag:blogger.com,1999:blog-6780103924890350442.post-85877736554574222022014-10-30T19:52:09.609-07:002014-10-30T19:52:09.609-07:00Anon,
Some populations that are dwindling may eas...Anon,<br /><br />Some populations that are dwindling may easily become extinct so absolutely over-weeding is a concern. Here is an example -- one course of antibiotics in babies EXTINGUISHES ALL DETECTABLE Bifidobacteria adolescentis. This happens all the time sadly.<br /><br />"However, amoxicillin treatment induced a complete disappearance of Bifidobacterium adolescentis species (occurrence rate of 0% versus 36.4% in healthy group, P < 0.001), a significant decrease in the occurrence rate of Bifidobacterium bifidum (23% versus 54.5% in healthy group, P < 0.05)"<br />http://www.ncbi.nlm.nih.gov/pubmed/20601031<br /><br />Low bifido and soil probiotics are found in nearly every Western civ pathology. Trying to bring up all our native ancestral gut species is the end game because this is how we are set up. They protect and exclude pathogens but can only do so when there are enuf of them and in a collection that helps them thrive. They don't work alone -- they need each other, work collaboratively and crossfeed. If some are missing, others die.<br /><br />Yes so overweeding is as bad as antibiotics... as bad as single high dose RS2 or low fiber diets for diversity of the flora. Olive leaf has both antifungal and antimicrobial effects. Are you targeting just fungi because if so you may narrow the spectrum by using only antifungals (prescription ones). These may affect the liver but if indicated, they're more narrow in spectrum.<br />Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-90640498708762047362014-10-30T19:39:15.514-07:002014-10-30T19:39:15.514-07:00Guttural
Definitely -- Bryan suggested we try Aud...Guttural<br /><br />Definitely -- Bryan suggested we try Audacity. May double record on iphone too. Thanks for the tips!<br /><br />I love your supposition on the ancient pivot point on the human/R3 love story. What makes us human? hearts? empathy? dreaming/scheming? love? ahaha UR ON TO SOMETHING<br /><br />I deeply concur: "RS2 alone = Ape brain"Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-8184584420767408052014-10-30T18:23:16.288-07:002014-10-30T18:23:16.288-07:00Thanks for the reply re neem and over-weeding. Wil...Thanks for the reply re neem and over-weeding. Will certainly make sure to keep up the probiotics!<br /><br />Sorry one more, do you think Olive Leaf can potentially over-weed too? There is something in it which kills something that nothing else seems to touch. Whenever I haven't taken it for a little while, as soon as I have it there is a little bit of die-off. I can't get to whatever the root cause is and kill it off for good. <br />Hoping that this use of it doesn't over-weed though. <br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-39824324589344478392014-10-30T17:31:49.520-07:002014-10-30T17:31:49.520-07:00Sound drops out too much. Record audio locally at ...Sound drops out too much. Record audio locally at both ends and mix it together.<br /><br />--<br /><br />With the whole 'cooking lead to our bigger brains' thing, does that also make it the start of the Human/RS3 love story? RS2 alone = Ape brain!Gutturalnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-26034768123397575682014-10-30T16:24:53.982-07:002014-10-30T16:24:53.982-07:00Anon
To adequately address the satellite organs, ...Anon<br /><br />To adequately address the satellite organs, the full body FARM-acy approach and heavy probiotic dosing is key I believe. Let me know what works for you.<br /><br /><br />Stephen, Larch AG is great. Which brand are you using? What do you notice? better brain-gut? better bristols? Larch seems to enable better immunity. Have you done testing? What is your gut missing? Which 'fingerprint' did you fit into?<br /><br />Part 1: <a href="http://drbganimalpharm.blogspot.com/2014/09/dont-take-resistant-starch-alone-and.html" rel="nofollow">Don't Take Resistant Starch Alone and Other Precautions; RS2 Needs to Be Taken With Other Fiber To Spread Fermentation Completely Across the Entire Colon</a><br />Part 2: <a href="http://drbganimalpharm.blogspot.com/2014/09/dont-take-resistant-starch-alone-part-2.html" rel="nofollow">Real Food Resistant Starch (RS3) Trumps High-Dose Potato Starch Diet To Expand the Lean and Immunoprotective Core Microbiota (Roseburia, Eubacteria, F. prausnitzii, Bifidobacteria)</a><br />Part 3: <a href="http://drbganimalpharm.blogspot.com/2014/10/dont-take-raw-resistant-starch-if-you.html" rel="nofollow">Don't Take Resistant Starch If You Have Moderate to Severe Irritable Bowel Syndrome (IBS) Temporarily</a><br />Part 4: <a href="http://drbganimalpharm.blogspot.com/2014/10/dont-eat-raw-resistant-starch-rs2-if.html" rel="nofollow">Don't Eat Raw Resistant Starch (RS2) If Pre-Cancerous or Cancerous for Colorectal Cancer, Temporarily </a><br />Part 5: <a href="http://drbganimalpharm.blogspot.com/2014/10/dont-take-raw-potato-starch-rps.html" rel="nofollow">Don't Take Raw Potato Starch (RPS) Temporarily If You Have an Autoimmune Disorder</a><br /><br /><br /><br />Anon, Yes overweeding needs to be balanced and not happen lol if possible. If one is properly seeding all along, I doubt it will happen but certain botanicals certainly will affect tender bifido and soil probiotic populations.Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-88812614858384143512014-10-30T16:20:47.716-07:002014-10-30T16:20:47.716-07:00Esha
Sounds like a great plan -- antibiotics real...Esha<br /><br />Sounds like a great plan -- antibiotics really are the factor for our current mass (gut) extinctions. So to combat, heavy probiotics and healthy soil/plant/environmental exposures (FARM-ACY) is really the only solutions until little poo pills come along!<br /><br />Isn't that ABSOLUTELY WILD? I love your humate/probiotic combo. That is similiar in concept but diff strains as the prescript assist.<br /><br />Have you considered non-dairy probiotics? Until the gut is fully healed, diary is one of the top 5 worse food allergens. Stopping until at least until the gut is properly seeded/weeded usually yields results 10 to 20-fold faster. no jokeDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-50982522532305448722014-10-30T01:23:18.806-07:002014-10-30T01:23:18.806-07:00Dr BG, I've just ordered some neem leaf and lo...Dr BG, I've just ordered some neem leaf and looking forward to seeing how it goes. A little question though, do you think it would be a bad thing to take regularly, could I inadvertently over-weed?<br /><br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-29048324917456272572014-10-29T14:37:59.511-07:002014-10-29T14:37:59.511-07:00i seem to tolerate larch arabinogalactan very well...i seem to tolerate larch arabinogalactan very well. what's the smartest way to use this? what other fiber supplements will complement it best to help foster a more diverse and healthy biome?<br /><br />thanks in advance!Stephennoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-69166522769989233202014-10-29T12:32:43.380-07:002014-10-29T12:32:43.380-07:00Grace,
I’m reading the link, about humates. It’s ...Grace,<br /><br />I’m reading the link, about humates. It’s shocking perhaps... but my favorite Bacillus subtilis (i use 2 strains) comes from a fertilizer... It consists only of humates and Bacillus subtilis spores. I use it for flowers and once on an impulse i licked it and ate a little... thought i was going to get sick or something, but it turned out that my body loved it much more than Bacillus subtilis for humans. Dirt cheap and helps a lot, but i was very uneasy about humates and tried to find something equally effective among regular probiotics. It looks like i do address mercury after all...Eshanoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-31749383606494868362014-10-29T11:40:11.042-07:002014-10-29T11:40:11.042-07:00Oops. I mean the good guys!Oops. I mean the good guys!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-10362993542349496902014-10-29T11:39:21.171-07:002014-10-29T11:39:21.171-07:00You mentioned hidden candida in bladder and vagina...You mentioned hidden candida in bladder and vagina . What do you recommend to address these areas without damaging the good gut flora we are trying to establish? I need to address stubborn infections in these areas without killing out the god guys. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-31675388537900934412014-10-29T11:39:06.289-07:002014-10-29T11:39:06.289-07:00Grace, thank you for your answer and the link!
It...Grace, thank you for your answer and the link!<br /><br />It’s not mercury, but tons and tons of antibiotics since early childhood... babyhood even. I’m going slow with candida as nearly all anti-candida stuff makes me awfully constipated. On the other hand Bacillus subtilis (an ordinary strain, not the interferon-producer) and bidobacteria lactis help to keep it at bay and peristalsis is ok. Now I’m getting more aggressive and add coconut oil, garlic and spices and sometimes clay but i’m always careful not to overdo the killing... Die-off constipation is too much for me and the only way out is to take yogurts with LGG or l. casei. They help the gut but ironically... worsen candida!! Plus my sinusitis reacts to l. bulgaricus, acidophilus, streptococcus and these strains are everywhere. It’s like a vicious circle: candida – antifungals – constipation – yogurts (in bad cases + flaxseeds + raw potatoes) – constipation resolved – candida + brain fog + stuffy nose... <br /><br />I plan to try more SBO probiotics, even for animals, perhaps... it’s cheaper that way and easier to get... and little by little incorporate antifungals...Eshanoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-1782860477001827482014-10-29T06:55:14.539-07:002014-10-29T06:55:14.539-07:00Esha,
The GMOs probiotics (many out there and par...Esha,<br /><br />The GMOs probiotics (many out there and particularly in the yogurts Activia, etc) really creep me out. Several cancers already have high levels of IFN, TNF or IL10. More is not better.<br /><br />Soon however there will be strains that are better for different conditions. They are like people -- different talents, strengths and weaknesses. They like other people -- to form communities. So I believe there will later be very intense systems biology to 'match' certain probiotics to the baseline gut composition to speed gut recovery. I believe we will get there in the next 10 years.<br /><br />Have you checked out ways to lower candida? Have you addressed mercury? Don't overlook 'secret' reservoirs of candida -- bladder, vagina, sinuses and brain. Sinuses respond well to olive leaf extract and Argentyn nasal rinses. I believe this will aid the brain-gut.<br />http://www.medicalinsider.com/bacterial.htmlDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-56274236981354990812014-10-29T04:26:59.142-07:002014-10-29T04:26:59.142-07:00I’m fine with RS3, garlic and onions (i absolutely...I’m fine with RS3, garlic and onions (i absolutely adore garlic), but chicory drink caused a flare-up of candida, that seemed pretty much under control :( So i stepped back, reintroduced coconut oil and Bacillus Subtilis and explore locally available probiotic options (SBO). Bacillus amyloliquefaciens is definitely on the list and i’m a bit doubtful about enterococcus faecium (bad reaction to streptococcus thermophilus) and this interferon-producing Bacillus.Eshanoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-52504329153889250632014-10-29T02:53:08.717-07:002014-10-29T02:53:08.717-07:00Hi, Dr BG :)
Grace, what’s your opinion on Bacil...Hi, Dr BG :) <br /><br />Grace, what’s your opinion on Bacillus Subtilis genetically modified to produce human interferon alpha 2? It’s available in my country and advertised as highly effective for lot’s of conditions...<br />Eshanoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-71290586285001044812014-10-28T17:07:12.440-07:002014-10-28T17:07:12.440-07:00Anon,
This is huge spam -- someday I'll have ...Anon,<br /><br />This is huge spam -- someday I'll have a post but Matt and I discuss briefly on a podcast later. <br /><br />If two conditions, (1) you mix with a significant and substantial dose of other fibers that feed B longum + ancestral core and (2) B longum + core not stunted or reduced by the treatment <br /><br />(so analysis via fecal testing is required via Genova diagnostics if possible -- ubiome and amgut don't test to this level of species detail, only phyla).<br /><br />What potato starch feeds are the 'animal' species of bifido -- none of the authochthonous (native) human strains (except B lactis which is generally super low in #). <br /><br />B longum is key because it's one of the first to be depleted in illness or gastroenteritis and/or antibiotics. B longum makes about 68-75% of healthy mucosa bifido microbiota, in other words, it is truly the stalwart gut guardian!<br />http://aem.asm.org/content/75/6/1534.full.pdf+html<br /><br /><br />The problem is that PS lowers B longum which is the main bifido in healthy humans. Instead PS highly and selectively feeds animal species -- animalis, lactis, pseudolongum, etc. See Fig S3 in supplemental.<br /><br />"Bifidobacterium animalis was specifically enriched in mice fed 36% HAM-RS2, and this species was previously shown to degrade certain RS formulations with greater efficiencies than species pseudolongum and breve (Wronkowska et al., 2008). Overall, these results support the concept of concentration-dependent effects of dietary substrates on the gut microbiota and the importance of consuming RS and prebiotics in concentrations that induce optimal levels of intestinal fermentation and host-microbe cell signaling (Davis et al., 2010)."<br />http://www.ncbi.nlm.nih.gov/pubmed/22909308<br /><br />(i don't like mice studies -- this doesn't one fails to translate either -- humans do not increase Akkermansia with RS2; I don't see it on testing and the below n=1 did not either)<br /><br />PS also lowers nearly ALL THE ANCESTRAL CORE. <br /><br />If you exam data from RS2 animal studies, all fail to translate to human improvements in human disease states. I like RS2 -- it has a place but for guts that are missing vital strains, it skews toward a hamster profile which I find unacceptable if one is trying to optimize the barrier function, leanness, insulin sensitivity and longevity. <br /><br />Lastly, here is an n=1 and though diet was 10-20 g RS3 (cooked cooled) PHD style 150 grams/day starch diet with vegetables/fiber, a profile that was low on the butyrate factories (XIVa) and Akkermansia was evoked. Again, failure to translate. <br /><br />http://drbganimalpharm.blogspot.com/2014/09/dont-take-resistant-starch-alone-part-2.htmlDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-59214063195237574502014-10-28T16:04:46.596-07:002014-10-28T16:04:46.596-07:00im confused, why no potato starch? what if we mix...im confused, why no potato starch? what if we mix with other fibers?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-18892155834748019462014-10-28T14:18:28.453-07:002014-10-28T14:18:28.453-07:00Grace, thanks for the clarification on Pectin. The...Grace, thanks for the clarification on Pectin. There remains a whole lot to be learned!<br /><br />- NilsAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-8185829686600782432014-10-28T13:12:01.088-07:002014-10-28T13:12:01.088-07:00DR. V
https://www.gdx.net/core/interpretive-guide...DR. V<br /><br />https://www.gdx.net/core/interpretive-guides/GI-Effects-IG.pdf<br /><br />The new testing shall show people. What I like about this is that at the species level Bifidobacteria longum and several others will be quantified. The right flora, lifestyles, diet and fiber/prebiotics will bring the composition that now is trackable, and these mimic perhaps the ancestral core. It is not difficult to bring these core strains up (IF THEY ARE THERE!)<br />--heavy RS3 (no potato starch)<br />--heavy inulin/fiber diet, whole foods if possible<br />--probiotics to seed, +FARMACY<br /><br />This has been the key that works for many. Inulin resistance improves and body fat melts lol (if that is the desire).<br /><br />I've not heard anything on the grapevine about 're-poop-ulate' synthetic probiotics yet. It would make a great business.<br /><br />Thanks -- kraut with some poop, the vital ancestral core would be great! Great idea!! lolDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-2402646757995127022014-10-28T13:08:11.645-07:002014-10-28T13:08:11.645-07:00Sorry Nils -- almost forgot pectin again. Pectin i...Sorry Nils -- almost forgot pectin again. Pectin is the baseline fiber in nearly every high fiber food from legumes, fruits, berries to beets. Hard to miss if you follow (7 steps) or just a high fiber diet, so I don't bother mentioning it! Thanks for bringing it up. Pectin is even found in potatoes but low amounts.<br />http://link.springer.com/article/10.1007%2FBF02855866<br /><br />By eating whole, unrefined foods your gut will thank you and work harder. Diversity of fiber breeds diversity of the flora, naturally. Pectin is part of NSP and if you eat whole RS3 foods then pectin is part of the fiber spectrum. RS3 feeds almost the entire gut including the ancestral core, and the add'l pectin, arabinoxylan and hemicellulose that accompany the plant structure bolster or feed the rest.<br /><br />http://drbganimalpharm.blogspot.com/2014/06/contupdate-2-rs2-and-rs3-are-not.htmlDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-50434389876742657242014-10-28T12:48:38.814-07:002014-10-28T12:48:38.814-07:00Nils
Thanks for the paper! I know in baking, acid...Nils<br /><br />Thanks for the paper! I know in baking, acid base is needed for non-yeast baking. I wonder if the pH is above 5 for the inulin to not breakdown in baked goods with 1-2 tsp baking powder, which is what I use? If so, then probably would be fine. Wonderful!Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-49328352043799911492014-10-28T06:47:13.558-07:002014-10-28T06:47:13.558-07:00Hi Grace,
Love your blog!
Before on the podcast ...Hi Grace,<br /><br />Love your blog!<br /><br />Before on the podcast (don't remember which one, sorry!) you mentioned Inulin breaks down during heat. This paper http://www.food.actapol.net/pub/5_2_2011.pdf seems to dismiss that notion, stating that rather than heat the pH (lower = more breakdown) is the most important factor.<br /><br />Question: YOu almost never seem to mention pectin, is it just unimportant in feeding key species?<br /><br />Thanks! NilsAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-28918456228149409952014-10-28T06:38:59.854-07:002014-10-28T06:38:59.854-07:00Thanks for super blog... :) Thanks for super blog... :) Hakkinda Bilgihttp://hakkindabilgial.comnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-27937294420896550452014-10-28T05:53:39.704-07:002014-10-28T05:53:39.704-07:00http://1.bp.blogspot.com/-3eHTGWCdTGA/UjWVp1dHg7I/...http://1.bp.blogspot.com/-3eHTGWCdTGA/UjWVp1dHg7I/AAAAAAAABaU/d6RT6JogUVI/s1600/GI+FX+DR.BG+microbiome.png<br /><br />Hi Grace. Thx for reply. I see your results. Do they go into detail to see if you regained Roseburia or Akkermansia and stuff?<br /><br />Maybe you can bottle some good fermented veggies with the good guys and a start a side business :)<br /><br />Anyways following you on twitter now. How long do you think before something like Repoopulate becomes commercially available? <br /><br />Dr VAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-32041737125888995702014-10-27T06:27:46.682-07:002014-10-27T06:27:46.682-07:00Grace,
Thanks for sharing your thoughts.
Yesterd...Grace,<br /><br />Thanks for sharing your thoughts.<br /><br />Yesterday when I was "harvesting" some dandelion roots in a huge garden which is more like a forest than a classic garden the following came to my mind:<br /><br />When I buy carrots with some dirt still on it, the dirt is only soil (sand). But the dirt on the dandelion roots is much more diverse: it's soil and composting or already composted dirt. So I went to a huge nearby organic farmfield and did some digging. I only found sand and noting else. But in the garden the soil is filled with all kinds of composting stuff. So my guess is that the soil in the garden is much closer to ancestral soil then most farmlands and the SBO's in there are more diverse.<br /><br />Conclusion: it's better to lick a dandelion root then a carrot in this case.<br /><br />DanielAnonymousnoreply@blogger.com