tag:blogger.com,1999:blog-6780103924890350442.post7394338777115832399..comments2023-11-30T00:29:08.106-08:00Comments on Animal Pharm: Insulin and Aging: How Paleo WorksDr. B Ghttp://www.blogger.com/profile/15451872961651116061noreply@blogger.comBlogger46125tag:blogger.com,1999:blog-6780103924890350442.post-40400051124984945832010-07-06T08:57:45.164-07:002010-07-06T08:57:45.164-07:00"Indeed. I used to consume that much at break..."Indeed. I used to consume that much at breakfast (high carb, low fat Nutri-grain 'breakfast' bar and cup of industrial low fat bGH n-6 milk) -- then have horrible panic attacks, rushed heart rate, irregular skipped heart beats at night, mild anxiety, stress intolerance, flushing and occ headaches. "<br /><br />BTDT. And then a couple of hours later I'd run out of energy even to the extent of falling down or passing out. Reactive hypoglycemia, which obviously didn't show up on an FBG, it took 50 years for a sensible GP to give me an OGTT.<br /><br />Since then with my glucometer I discovered I have little to no Phase 1 insulin but plenty of Phase 2 and can spike to 140 - 180 after a Heart Healthy meal, then drop to 60 - 70, several times a day. But I'm still "not diabetic" because I only hit over 200 when no-one else is looking.<br /><br />Paleo-type eating keeps my BG around 80 - 110 most of the time.<br /><br />According to users the Metfartin effect results from eating carbs which aren't absorbed so pass through.<br /><br />Gallstones? BTDT also. They're related to high cholesterol (from all those healthy carbs) and also to neuropathy from high BG preventing the gallbladder from contracting properly.<br /><br />When I had them fat would cause an attack a few hours later as stones passed throguh the bile duct while I writhed in agony on the floor praying to die for several hours. <br /><br />After cholecystectomy I've had no problem eating fat, except for blocking the bog occasionally, my current turds sink instead of floating. Meat, fish, cheese and vegetables obviously contain enough fibre without the hassle of bran.<br /><br />Also I no longer blow off like a carthorse.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-40640725821058096382009-12-23T07:50:13.145-08:002009-12-23T07:50:13.145-08:00update re butyrate breath: a "confounding fac...update re butyrate breath: a "confounding factor" was discovered last night -- my kid's school lunch box containing leftover bits of raw broccoli, which had been sitting (festering) behind the door since the holdiay break started. Hoo-doggies, what a reek! <br /><br />The butyrate is innocent!caphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-66672088507319915262009-12-22T12:17:51.880-08:002009-12-22T12:17:51.880-08:00I will try freezing. I hope it stops eau de butyra...I will try freezing. I hope it stops eau de butyrate from being exhaled in the breath.caphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-16415004669611030112009-12-22T10:51:07.124-08:002009-12-22T10:51:07.124-08:00caphuff,
They smell awful, don't they?! Here&...caphuff,<br /><br />They smell awful, don't they?! Here's a tip that I learned early on: Keep the butyrate pills in the freezer. It really does help.<br /><br />DavidDavidhttps://www.blogger.com/profile/12920771116773938946noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-7635829156425075012009-12-22T06:39:15.883-08:002009-12-22T06:39:15.883-08:00Something to consider for anyone thinking of suppl...Something to consider for anyone thinking of supplementing butyrate: since commencing same the wife complains my breath stinks up the bedroom something fierce. Those butyrate pills do have a rather nasty odor to them. (Somewhere between kibble and vomitus!) <br /><br />Maybe d-limonene would help in that department . . .caphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-82539716012694325642009-12-21T21:50:25.139-08:002009-12-21T21:50:25.139-08:00G,
The olive oil/lemon juice gallbladder flush i...G, <br /><br />The olive oil/lemon juice gallbladder flush is interesting. About 4 years ago, when I had Lyme, I had some severe gallbladder attacks. REALLY painful stuff. I did the olive oil/lemon juice thing and passed over 100 "stones" overnight. The attacks never came back.<br /><br />Now here's the weird thing. Awhile back, a case report came out in the Lancet that showed the "stones" from a similar flush to be basically nothing more than oleic acid and lemon juice -- i.e., <i>not</i> gallstones. However, there have been other case reports ('80s and early '90s; e.g. http://smj.sma.org.sg/2706/2706smj14.pdf) that showed this flush producing real gallstones. Who to believe? <br /><br />So I have mixed feelings about it. On the one hand, it's confusing as to how well it actually works across the board. On the other hand, it seemed to work really well for me (and I later had a gallbladder sonogram that showed no gallstones). *shrugs* Maybe good, but I really don't know for sure. <br /><br />DavidDavidhttps://www.blogger.com/profile/12920771116773938946noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-57043817423289576542009-12-21T15:10:07.731-08:002009-12-21T15:10:07.731-08:00Hey!
I don't know what limone is but I just s...Hey!<br /><br />I don't know what limone is but I just saw a patient earlier this wk who reported that gallbladder surgery was pending, she had terrible pain and discomfort. Her husband found a 'remedy' using juice of 1/2-1 lemon with 2 Tbs olive oil. She did that for 2-4wks then all her pain was gone and the surgeon ended up cancelling the surgery. She things she is gluten-intolerant as well (not celiac but on the spectrum).<br /><br />Interesting huh? I don't if the fatty acids in olive oil help emulsify. Olive is 15% saturated fatty acids as well.<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-9963055792215250392009-12-21T13:42:42.758-08:002009-12-21T13:42:42.758-08:00I've also wondered about oral d-limonene, and ...I've also wondered about oral d-limonene, and haven't been able to find much info. I'm just going off my own observations with a couple different people. Coincidence or not, it seemed to work well (and quickly). In any case, I don't think it will hurt. Up to you, though.Davidhttps://www.blogger.com/profile/12920771116773938946noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-84278725267552097672009-12-21T12:32:47.248-08:002009-12-21T12:32:47.248-08:00also, not to keep harping on gallbladders, but Pet...also, not to keep harping on gallbladders, but Peter at Hyperlipid (back in 2008)blogged on the likely gluten connection. Very interesting.<br /><br />http://high-fat-nutrition.blogspot.com/2008/06/gluten-and-gall-bladders.htmlcaphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-14584169825849170742009-12-21T07:08:10.718-08:002009-12-21T07:08:10.718-08:00David: thanks for the tips.
d-limonene looks int...David: thanks for the tips. <br /><br />d-limonene looks intriguing, though a quick google gave a lot of hits on injecting the stuff directly into the GB to achieve stone-dissolution. Wondering how effective a delivery method oral supplementation would be. Would enough of it find its way in there to start working its magic?<br /><br />In any case, the butyrate experiment continues apace with no further complaints, as yet.<br /><br />Dr. BG: yes, I ate the bun! That (and the fries and coke) was probably the main offender, there. Hope the old jewel bag was not too roughed up by it.caphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-8289125854273581762009-12-19T11:22:17.945-08:002009-12-19T11:22:17.945-08:00caphuff,
I really doubt the butyrate had anything...caphuff,<br /><br />I really doubt the butyrate had anything to do with the gallbladder discomfort. Butyrate is good for the gallbladder and shouldn't be a problem. The Burger King explanation seems much more likely. :) Keep me updated as to how you do with the butyrate. I'm really curious to see if others have similar experiences as mine.<br /><br />I totally agree with G as to the digestive enzyme suggestion. If the gallbladder stuff continues, you might try taking some extra taurine and see if that helps. Also, look into d-limonene. I've seen gallbladder pain completely resolve after just a couple weeks of taking d-limonene. Look for the Jarrow brand, as it's good quality and yet super inexpensive.<br /><br />DavidDavidhttps://www.blogger.com/profile/12920771116773938946noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-20421449683545473002009-12-19T02:28:03.808-08:002009-12-19T02:28:03.808-08:00What relationship is there between insulin spiking...What relationship is there between insulin spiking and elevated fasting inslin. A mouse study showed mice on a high-fat diet had elevated fasting insulin. I am always sceptical of these mouse studies, but it seems it does not follow necessarily that insulin spiking is the cause of elevated fasting insulin.<br /><br />Regarding butyric acid, the fatty acid profiles I have seen for cheese, cream and whole milk yoghurt are also quite high in butyric acid. Indeed, I find that after having several samples of my artisan cheeses in the mmorning, I have abundant energy and have more power for a morning kayak, mountain bike or road bike outing.<br /><br />MurrayAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-82236761407561782252009-12-18T17:26:18.404-08:002009-12-18T17:26:18.404-08:00caphuff,
*whooo* I'm so relieved your poo doe...caphuff,<br /><br />*whooo* I'm so relieved your poo doesn't float :)<br /><br />I used to be addicted whopper #3 w/fries and orange soda... extra mayo (n-6 pufas). <br /><br />You ate the bun didnt you??! <br /><br />I believe you are entirely correct -- it is mainly gluten and grains that trigger most GB issues. GB and stones are related autoimmune disorders. Someday I'll get a post out. Do you know what paid for college for me and my sisters? My dad is a surgeon and he did A LOT of choley's (and still does). *haa* He describes a healthy as velvety, nice, greenish, glassy looking like a jewelbag. The diseased ones are stonelike, hard. Calcified/fatty.<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-44555491914760161332009-12-18T14:43:53.135-08:002009-12-18T14:43:53.135-08:00Except my 'stones were first diagnosed years a...Except my 'stones were first diagnosed years ago after a lifetime on the Standard American Diet (if decades of sugary breakfast cereals and staggering amounts of sugar in my coffee is "standard").<br /><br />If fat was the contraindicative guilty party then I'd have expected my GB to start complaining straight away when I cut down on the carbs sugar and replaced those calories with fat. <br /><br />Instead, despite the onslaught of fat I've been pumping through the sluices for the past 5 or 6 months, the only twinge of GB distress came after an ill-considered fast-food meal that happened to coincide with butyrate supplementation. (Not to tar butyrate with the same feathers as a BK number 1 combo, or anything.)<br /><br />Also, my poo doesn't float.caphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-83910442320982135052009-12-18T13:55:53.057-08:002009-12-18T13:55:53.057-08:00WHOPPER...!? ;)
One of the 'contraindications...WHOPPER...!? ;)<br /><br />One of the 'contraindications' for a mod-high fat diet can be steatorrhea (fatty stools) and lack of gallbladder function. Bile acids (and lipases) are nice to have around to emulsify the fats for digestion.Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-59136772697167999152009-12-18T12:43:04.898-08:002009-12-18T12:43:04.898-08:00Thanks for the suggestion Dr. BG.
Well, I've ...Thanks for the suggestion Dr. BG.<br /><br />Well, I've been taking probiotics lately, and papaya enzymes have always been a tried and true friend of the old GI tract. <br /><br />But gallstones oddly haven't really been an issue since cutting out sugar and wheat, going (more or less) low carb, and upping the fat intake(primarily through heavy cream, tee hee!)I say oddly because liberal fat intake would seem to go against the CW for gallbladder issues, no?<br /><br />Anyway, this morning's episode could also have been kickback from eating at Burger King the other day (knew I shouldn't have done that, but it was all in the interest of science!) Maybe butyrate is a red herring. It was the whopper, in the car, with the fructose.caphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-45433573739219089032009-12-18T11:51:19.184-08:002009-12-18T11:51:19.184-08:00caphuff,
Have you ever considered the value of di...caphuff,<br /><br />Have you ever considered the value of digestive enzymes? They contain lipases, amylases and other complex enzymes which aid in the proper breakdown and metabolism of food. It can be helpful when the gallbladder/pancreas/biliary tree is affected.<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-88700941362030950672009-12-18T11:49:54.960-08:002009-12-18T11:49:54.960-08:00lightcan,
BTW Is wt loss a goal for you? If you ...lightcan,<br /><br />BTW Is wt loss a goal for you? If you are considering further weight loss, consider a strict Paleo plan (dairy-free). It further reduces inflammation for many people (works for me too, when I do it).<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-42272802179924835722009-12-18T11:25:37.782-08:002009-12-18T11:25:37.782-08:00David,
well, curiosity got the better of me. I ju...David,<br /><br />well, curiosity got the better of me. I just got my first shipment of butyrate. (Bodybio brand, mag-cal formula).<br /><br />Took the first dose last night. Only effects to report yet, (other than a(maybe unrelated)slight increase in dream recall) was some upper right abdominal discomfort this morning. Curious about that, due to a gallstone history, with occasional flare-ups in my (pre-LC/ high-fat!) past. <br /><br />Wondering if the extra butyrate may have kicked up some activity there, somehow.caphuffhttps://www.blogger.com/profile/17630921602227752611noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-6293360762565527862009-12-18T07:02:07.232-08:002009-12-18T07:02:07.232-08:00lightcan,
I'm so sorry about your previous ps...lightcan,<br /><br />I'm so sorry about your previous pst! I don't think I saw it (though replies go to the spam and have to be phished out).<br /><br />You know, I don't know if it is because of our female genes and hormones, but I don't process fats nearly as efficiently as the Paleo guys out there. Dairy makes me fat -- but for winter I don't mind as much the extra layer (sort of). We don't respond to intermittent fasting similarly sometimes too (in the clinical trials). <br /><br />It is the hormones.<br /><br />So -- actually from T-muscle (formerly T-nation.com) I found that the female figure athletes go high carb, low low fat on some days. They cycle the carbs. I found that this works for me as well -- if I am eating higher carb, I don't do so much fat. I also do better with more veggies. Have you ever read the 'why French women don't get fat'? Leek soup for 2-3 days is the way they 'intermittently fast'. Certain veggies have higher diuretic potential. The fiber also is anti-inflammatory (if one does not have gut issues or severe diverticulosis/-litis).<br /><br />Do you have any gut issues? Gas bloating heartburn? Probiotics and digestive enzymes actually play a role in LDL and LDL receptors (via LXR PPAR and bile acids).<br /><br />Also it's the holidays. Perhaps humans are meant to glycate to some extent? Then work it off without worry later... I take insulin sensitizing supplements -- they just help me b/c I appear to need it still. I feel more focused, clear-minded and less insulin-y. <br /><br />Yes regarding hormones. Hormones are the easiest way to sensitize insulin -- vitamin D, thyroid optimization, sex steroids.<br /><br />Have you read Cheryl Harte MD, Uzzi Reiss MD or Hyman MD? Their books are great resources for me. They believe and advocate bio HRT and optimization. <br /><br />Hope that helps!<br /><br />-GDr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-66401841907891884872009-12-18T06:49:14.622-08:002009-12-18T06:49:14.622-08:00*hee* David is free to takeover anytime! Thank yo...*hee* David is free to takeover anytime! Thank you per usual for sharing your big phat BRAIN :) I always learn an amazing TON of insights.Dr. B Ghttps://www.blogger.com/profile/15451872961651116061noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-2095672268579222262009-12-18T02:41:02.545-08:002009-12-18T02:41:02.545-08:00Hi Dr. G,
I replied to your questions but it seem...Hi Dr. G,<br /><br />I replied to your questions but it seems my post didn't go up. My weight is more or less stable for the last 4 months at 60 kgs for 1.68 cm. <br />I have some more questions. Seeing that the holidays are approaching and that the Christmas food is both high in sat fat and high glycemic carbs is there any advice you can give to a person with an LDL over 400? I suppose you'd say avoid refined sugar and roast potatoes and parsnips. If fats don't influence the absorption of sugar they shouldn't be used for that purpose, should they? I always make sure that if I eat anything remotely sugary I eat it after a low carb, high fat meal to prevent any spikes. Is it worth doing it? The glycation is still going to happen.<br />Do you think it's worth reducing my extra added saturated fat intake (butter on meat, double cream as dessert) to see my LDL go down as my doctor suggests? If I'm perimenopausal at 40 as you suggested what can be done? Hormone balancing?lightcanhttps://www.blogger.com/profile/03050215395108869677noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-32020960597361516882009-12-16T13:34:24.624-08:002009-12-16T13:34:24.624-08:00Ah, I see. I actually get pain in my intestines --...Ah, I see. I actually get pain in my intestines -- especially from grains. This is a different feeling than with gas and such. I'm not celiac, but I'm sure I am sensitive to gluten.Davidhttps://www.blogger.com/profile/12920771116773938946noreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-6231144853987107902009-12-16T11:27:57.175-08:002009-12-16T11:27:57.175-08:00Thanks for your response, David. I was wondering ...Thanks for your response, David. I was wondering what you meant by the "nasty feeling" you mentioned when you said "Also, while on the butyrate, I didn't have the usual nasty feeling (especially in my guts) I normally get from eating badly." <br /><br />If I were to eat fruit and french fries, I would get gas and bloating. But on a very low fiber, very low carb diet my digestion is fine.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6780103924890350442.post-79432818500173370202009-12-15T15:55:10.363-08:002009-12-15T15:55:10.363-08:00Anon,
Can't say from my experience whether it...Anon,<br /><br />Can't say from my experience whether it helps bloating and gas, as I don't really have those problems to begin with. Bad problems with gas might be from eating too many starches/carbs, and/or could be a malabsorption problem due to celiac, pancreatic insufficiency, lactose intolerance, etc. <br /><br />I used the magnesium/calcium butyrate formula from bodybio.com<br /><br />DavidDavidhttps://www.blogger.com/profile/12920771116773938946noreply@blogger.com