Lp(a) and Women's Heart Risks

For women with high Lp(a) and high CAC scores, estrogen (including natural, fake and the horsey-hormones) has been shown to in fact be beneficial in controlling CAD risk, events and reduction in Lp(a). Does this translate to men... *ha* I believe it may -- that is why alcohol-extracted soy protein, phytoestrogens and even... BEER help men with Lp(a) and reduce CAD.


With that said, controlling Lp(a) in post-menopausal women has enormous benefits for heart disease. HRT (hormone replacement therapy) is safe, convenient and promotes longevity and optimal heart health. Plus people report better well-being, sharper minds and unrelenting energy. (They say sex is better too.)

Bioidentical HRT and monitoring via salivary/blood testing is the ONLY way to go, according to my personal research.


Uzzi Reiss MD, Michael Colgan PhD, Suzanne Somers, Cheryle Hart MD (hormonesbyhart.com) are all excellent resources.

Each one of the above authors stress an insulin-controlled diet in conjunction with optimizing all 10 hormones (they forgot vit D -- but one of my pts sees Dr. Hart and she normalizes vitamin D [25-hydroxy-D] now).


1. Melatonin

2. DHEA

3. Pregnenolone

4. Estrogen (we have 3 types floating around -- E3 is the best and shown to be cancer protective; avoid E1, higher cancer rates)

5. Progesterone (Dr. John Lee MD obgyn is a good read esp for insulin, promotes avoidance of plastic/pesticides/poisons, etc)

6. Testosterone (yes for women this is very VERY good too -- and reduces Lp(a))

7. Insulin

8. Cortisol

9. Vitamin D

10. Thyroid



Control of Lp(a) is reviewed in great detail in our Part 3 TYP Diet, TYP Lp(a) reports 1 and 2.


Critical components of a successful Lp(a) reduction program at TYP are:

--control of all the above hormones -- ALL TEN

--good adequate sleep (for cortisol reduction and immune system optimization), rest, relaxation, recovery, etc

--exercise -- to reduce belly fat -- including resistance training which grows lean body mass, muscles

--low carb diet -- no wheat or gluten or grains or legumes; minimal fruit

--moderate diversely-colored nonstarchy veggies

--adequate high quality protein (including organic organ meats)

--avoidance of things which set off the immune system -- excessive cardio, excessive endurance training, infections, excessive mental or physical stress, sleep deprivation, etc

--antioxidants: astaxanthin, krill oil, carotenoids, coenzyme Q10, curcumin, alpha-lipoic acid, carnitine, NAC, flavonoids, pycnogenol, mushroom extracts, et cetera -- they are all EXCELLENT

--saturated fatty acids: unrefined coconut oil, MCT oil, fat on grassfed meat/wild game/free range fowl/wild seafood, egg yolks, butter oil (greenpasture.org), (if not casein-sensitive) raw fermented dairy, high-quality 70+% chocolate, organic lard, etc

--ultra high dose EPA DHA fish oil 6-8.5 grams daily (higher quantity, if inflammation is present)

--avoidance of all omega-6 refined veggie oils: sunflower, safflower, peanut, soybean, canola, etc

--intermittent fasting (this replicates the effects of NIACIN combined with all the above strategies)

--niacin 1-2 grams daily

--avoidance of low-fat diets (eg, the AHA low-fat-diabetogenic-kill-ya diet)



If elevated Homocysteine (greater than 8.0) occurs despite all the above strategies, consider adding high doses of B-vitamins
--Folic acid, 1 - 5 mg daily
--Vitamin B12, 1000 mcg daily (adenosyl- and/or methylated cobalamin) sublingual is the best absorbed form
--Vitamin B6, 50 mg daily
--Trimethylglycine (Betaine) 1.5 - 3 mg daily



Sure sounds like... the optimal Paleo warrior diet/lifestyle, right?

And... not unlike a diet/lifestyle of wolves...?