You know... it's like the ol' coyboys in my favorite Western movies who needed a few shots of WHISKEY to take away the PAIN when the bullets were taken out of the wounds...
I have to admit I can't stand house cleaning. Allergic is a good word. I don't have asthma any longer (thanks to TYP and therapeutic doses of Vitamin D3) but I'm still allergic... CAN'T STAND IT. Some of my best friends and neighbors have let their 'professional' help go recently (with the increase in costs from PETROL etc)... I let mine go a year ago after we moved... Boy... can you spell M-I-S-E-R-Y...???
Occasionally I'll do this trick and invite my most Martha-Stewart-girlfriends over for dinner. I figure they can SHAME me into cleaning... of course it works and the house will be sparkling clean for about 10minutes...
Unfortunately sometimes I invite my friends over and I get busy and fail to have time to clean. I just hope that I can get them liquored up and blur their vision to the dirt rings in the toilet and the dust accumulating... NNNNAAAWWWWTTTT... they DON'T IMBIBE... what was I thinkin??!
How can a family of 6 generate so much waste? And one cat? And several house spiders?
For one, I've been losing some hair (though reversing after stopping my DARN synthetic hormone LNg for birth control) so... yeah go ahead make the dog comparisons... I admit I shed... Long hairs ALL OVER THE DARN HOUSE.
How does our mammalian bodies handle waste and garbage? Is it pollution? Or does everything to some extent get recycled???
Co Q10 helps with recycling of crucial antioxidants and vitamins in our mitochondria and membranes. Coenzyme Q10 is a crucial component of the TrackYourPlaque program.
Other benefits include:
--Counters the depletion of Co Q10 that occurs with Statin use
--Reduces Lipoprotein (a) 12% -- Check out the TYP Report
--Recycles our natural antioxidants like Vitamin E, Glutathione, etc
--Reverses heart failure--Plays an critical role in anti-aging, neuroprotection, cardioprotection and reduction in hyperinsulinemia/diabetes/MetSyn
Curr Neurovasc Res. 2005 Dec;2(5):447-59.The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus.Dhanasekaran M, Ren J.
Division of Pharmaceutical Sciences, School of Pharmacy, University of Wyoming, Laramie, WY 82701, USA.
Coenzyme Q (ubiquinone, 2-methyl-5,6-dimethoxy-1,4-benzoquinone), soluble natural fat quinine, is crucial to optimal biological function. The coenzyme Q molecule has amphipathic (biphasic) properties due to the hydrophilic benzoquinone ring and the lipophilic poly isoprenoid side-chain. The nomenclature of coenzyme Q-n is based on the amount of isoprenoid units attached to 6-position on the benzoquinone ring. It was demonstrated that coenzyme Q, in addition to its role in electron transport and proton transfer in mitochondrial and bacterial respiration, acts in its reduced form (ubiquinol) as an antioxidant. Coenzyme Q-10 functions as a lipid antioxidant regulating membrane fluidity, recycling radical forms of vitamin C and E, and protecting membrane phospholipids against peroxidation. The antioxidant property, high degree of hydrophobicity and universal occurrence in biological system, suggest an important role for ubiquinone and ubiquinol in cellular defense against oxidative damage. Coenzyme Q-10 is a ubiquitous and endogenous lipid-soluble antioxidant found in all organisms. Neurodegenerative disorders, cancer, cardiovascular diseases and diabetes mellitus and especially aging and Alzheimer's disease exhibit altered levels of ubiquinone or ubiquinol, indicating their likely crucial role in the pathogenesis and cellular mechanisms of these ailments. This review is geared to discuss the biological effect of coenzyme Q with an emphasis on its impact in initiation, progression, treatment and prevention of neurodegenerative, cardiovascular and carcinogenic diseases.
Other illuminating references:
- Ernster L, Forsmark-Andrée P.
Ubiquinol: an endogenous antioxidant in aerobic organisms.
Clin Investig. 1993;71(8 Suppl):S60-5. Review.
PMID: 8241707 [PubMed - indexed for MEDLINE]
- James AM, Smith RA, Murphy MP.
Antioxidant and prooxidant properties of mitochondrial Coenzyme Q.
Arch Biochem Biophys. 2004 Mar 1;423(1):47-56. Review.
PMID: 14989264 [PubMed - indexed for MEDLINE]
- Mohora M, Katona E, Dinu V.
Pro- and antioxidant functions of quinones in mammalian cells.
Rom J Intern Med. 1999 Jan-Mar;37(1):3-14. Review.
PMID: 15523940 [PubMed - indexed for MEDLINE]
- Albano CB, Muralikrishnan D, Ebadi M.
Distribution of coenzyme Q homologues in brain.
Neurochem Res. 2002 May;27(5):359-68.
PMID: 12064350 [PubMed - indexed for MEDLINE]
- Shults CW.
Coenzyme Q10 in neurodegenerative diseases.
Curr Med Chem. 2003 Oct;10(19):1917-21. Review.
PMID: 12871093 [PubMed - indexed for MEDLINE]
- Ernster L, Dallner G.
Biochemical, physiological and medical aspects of ubiquinone function.
Biochim Biophys Acta. 1995 May 24;1271(1):195-204. Review.
PMID: 7599208 [PubMed - indexed for MEDLINE]
- Littarru GP, Tiano L.
Bioenergetic and antioxidant properties of coenzyme Q10: recent developments.
Mol Biotechnol. 2007 Sep;37(1):31-7. Review.
PMID: 17914161 [PubMed - indexed for MEDLINE]
- Navas P, Villalba JM, de Cabo R.
The importance of plasma membrane coenzyme Q in aging and stress responses.
Mitochondrion. 2007 Jun;7 Suppl:S34-40. Epub 2007 Mar 16. Review.
PMID: 17482527 [PubMed - indexed for MEDLINE]
- Siemieniuk E, Skrzydlewska E.
[Coenzyme Q10: its biosynthesis and biological significance in animal organisms and in humans]
Postepy Hig Med Dosw (Online). 2005;59:150-9. Review. Polish.
PMID: 15928598 [PubMed - indexed for MEDLINE]
- Ernster L, Forsmark P, Nordenbrand K.
The mode of action of lipid-soluble antioxidants in biological membranes. Relationship between the effects of ubiquinol and vitamin E as inhibitors of lipid peroxidation in submitochondrial particles.
J Nutr Sci Vitaminol (Tokyo). 1992;Spec No:548-51. Review.
PMID: 1297809 [PubMed - indexed for MEDLINE]
- Pobezhimova TP, Voinikov VK.
Biochemical and physiological aspects of ubiquinone function.
Membr Cell Biol. 2000;13(5):595-602. Review.
PMID: 10987383 [PubMed - indexed for MED INE]
- Beyer RE.
An analysis of the role of coenzyme Q in free radical generation and as an antioxidant.
Biochem Cell Biol. 1992 Jun;70(6):390-403. Review.
PMID: 1333230 [PubMed - indexed for MEDLINE]
- Nohl H, Gille L, Staniek K.
The biochemical, pathophysiological, and medical aspects of ubiquinone function.
Ann N Y Acad Sci. 1998 Nov 20;854:394-409. Review.
PMID: 9928447 [PubMed - indexed for MEDLINE]
- Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J.
Free radicals and antioxidants in normal physiological functions and human disease.
Int J Biochem Cell Biol. 2007;39(1):44-84. Epub 2006 Aug 4. Review.
PMID: 16978905 [PubMed - indexed for MEDLINE]
- Nohl H, Gille L, Kozlov AV.
Antioxidant-derived prooxidant formation from ubiquinol.
Free Radic Biol Med. 1998 Oct;25(6):666-75.
PMID: 9801066 [PubMed - indexed for MEDLINE]
- Merlo Pich M, Castagnoli A, Biondi A, Bernacchia A, Tazzari PL, D'Aurelio M, Parenti Castelli G, Formiggini G, Conte R, Bovina C, Lenaz G.
Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress.
Free Radic Res. 2002 Apr;36(4):429-36.
PMID: 12069107 [PubMed - indexed for MEDLINE]
- Shults CW.
Therapeutic role of coenzyme Q(10) in Parkinson's disease.
Pharmacol Ther. 2005 Jul;107(1):120-30. Epub 2005 Apr 21. Review.
PMID: 15963354 [PubMed - indexed for MEDLINE]
- Wold LE, Muralikrishnan D, Albano CB, Norby FL, Ebadi M, Ren J.
Insulin-like growth factor I (IGF-1) supplementation prevents diabetes-induced alterations in coenzymes Q9 and Q10.
Acta Diabetol. 2003 Jun;40(2):85-90.
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Function of coenzyme Q in the cell: some biochemical and physiological properties.
Physiol Res. 1995;44(4):209-16. Review.
--Organ meats: heart, liver, etc
--Fish, seafood, mollusks
--Meat: grass fed meat, poultry