Thursday, December 31, 2009

Happy New Year! 10 Gifts of Evolution

Nick Lane Does It Again
Life Ascending is Lane's latest (and greatest). He summarizes his thoughts on the 10 greatest inventions of evolution and reviews the evolutionary history, geology, plant and animal kingdoms of planet earth. Unlike the 2005 publication Power, Sex, Suicide: Mitochondria and the Meaning of Life which took me a year to read (?wtf I s*ck), this one is breezably less biochemy and a fascinating, intriguing, critically-thought out read. In fact I am almost DONE. It ties in much of the evolutionary thoughts that Mr. Billy E., Dr. Tourgeman and I have reviewed on the blogs regarding genetic expression, nutrigenomics, longevity/ aging/ death, chronic diseases like (kidney disease, heart disease, diabetes and other age-related diseases) and DISEASE REVERSAL. Mr. Lane believes diseases are reversible by control of of certain genes (gerontology- related genes elucidated from C. elegans (nematodes)) which have homology across phyla.

The Ten Gifts
1. The Origin of Life
2. DNA
3. Photosynthesis
4. The Complex Cell
5. SEX
6. Movement
7. Sight
9. Consciousness
10. Death

Guess what chapters I immediately skipped to ???!

Another Rolling Stones classic (omg too cute): As Tears Go By

One More... mp3 Player...


Sweat all over the MP3 player again, my like 5th or 6th in like 8-9 yrs, which finally frizzled out and BROKE.

What do you guys use?

Sunday, December 6, 2009

Insulin and Aging: How Paleo Works

Ai M showed the disparity between insulin changes between oral glucose loading (75 grams glucose) versus a high saturated fat CREAM dosing.

Carb equivalents 75 grams = 5 servings CARBs

Go to for more comparisons.

1 serv CARB = 15 grams

Dairy -- 1 cup milk = ~15 g

Fruit -- 2 bites is about 15 grams (small palm-full).

Grains (~ 15 grams):
Oatbran 1/3 cup. Oatmeal 1/3 cup. Bread 1 slice or half-slice depending on the density. Rice 1/3 cup. Pasta 1/3 cup. Broccoli 2-3 cups just kidding but infinitely more compared with grains which have an insanely high-carb density as well as genetic propensity to trigger stress, glucocorticoid and the expression of other 'bad' genes. See prior animal pharm FUNGENUT post HERE.

Legumes (~15 grams):
1/2 cup beans

Ai M et al. Clinica Chimica Acta 387 (2008) 36–41. Email me for the PDF if desired.

What is PALEO?
None of the above
--no dairy (except casein-free clarified butter/GHEE or whey protein)
--no grains (corn, oats, gluten (wheat/barley/rye), rice, etc)
--no legumes (beans, soybeans (unlesss soaked+fermented), peanuts)

Please see recent NephroPal post:
Insulin and Aging: How Paleo Works

Click above link...