|I asked two different companies to analyze my gut microbiome. American Gut (left) gave nearly opposite results to those from uBiome (right) with respect to the major phyla of bacteria in a duplicate sample.|
For more gut stool analysis consider the following functional medicine labs:
Stool -- Genova Diagnostics, Biohealth, Great Plains, Doctor's Data, etc
Urine -- Genova Diagnostics (ONE, Nutri Eval, Organix, etc)
The stool testing gives a partial view of what's inside that the Am Gut and uBiome lack -- protozoa, helminths, parasites, pathogenic yeasts, fungi, and the pathogenic bacterial overgrowths compared with symbiotic, beneficial commensal populations (E coli, Bifido, Enterococcus, Lacto, SBOs, etc)
Urine testing gives a partial view of what's going out of the gut
Caveat: all the current testing is imperfect including functional medicine testing, but what they can reveal are the (more stable) pathobionts and yeasts, which usually survive and thrive once colonization resistance and gut barriers are no longer functioning well or at all. Recently 16S pyrosequencing was done as part of the Ribosomal Database Project (RDP) on a sample of healthy Korean gut microbiota. Geographical differences were seen compared to other Asian and American countries however between Korean guts, there was homology and core phylogenetic similarities.
In 8 Koreans (below), their guts were tracked monthly for 3 time points. Temporally, great shifts are notable on nearly every gut. I think it indicates clearly that our gut is like a playground. Kids, toddlers, nannies and teenagers all vie for spots and it's constantly shifting over time. Studies show even between meals, the microbiota show significant shifts. A diet protocol can shift populations in only day.
|Temporal Month-to-Month Microbiota Shifts|
Korean RDP, 2011